The Translational Liver Research (TLR) group focus on liver disease-related research with major interest on three core themes:
Understanding the underlying disease mechanisms and cellular crosstalk in liver diseases;
Development of Targeted nanotherapeutics/nanotheranostics for diagnosis and treatment of liver diseases; and
Development of human disease mimic platforms for disease modelling and drug discovery.
The combination of fundamental studies with drug discovery and application-oriented research summarizes the crossover of different biomedical disciplines present in our group. The three research themes are interdependent and cover the complete knowledge chain from understanding diseases to designing theranostics and validating in different developed platforms (from in vitro cell culture, in vivo preclinical models to human disease-mimic models). By use of in vitro and in vivo techniques in cooperation with partners in academia and industry we aim for translational medicine in order to improve clinical applications and the quality of life of patients.