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Dhadhang is currently a PhD student at the University of Twente, within the Translational Liver Research group. He obtained his bachelor degree from School of Pharmacy Institut Teknologi Bandung, Indonesia. Since April 2006, he was a lecturer at Department of Pharmacy Universitas Jenderal Soedirman, Indonesia. Besides lecturing, he has also performed research related to pharmaceutical technology field. At 2011, he graduated from Master Program at the Faculty of Pharmacy Universitas Gadjah Mada, Indonesia. His master thesis was focused on the synthesis of thiolated chitosan as a matrix for the preparation of metformin hydrochloride microparticles. Since 1 February 2016, he joined as a PhD student at the University of Twente, The Netherlands. ORCID: LinkedIn:
Dhadhang is part of the ‘Targeted (nano)therapeutics/(nano)theranostics for diagnosis and treatment of liver diseases’ and 'Understanding the underlying disease mechanisms and cellular crosstalk in liver diseases' research topic within the Translational Liver Research group. Liver diseases is a growing health problem with a worldwide mortality of around 1.5 million death per year attributable to cirrhosis and hepatocellular carcinoma. Most of the liver diseases such as chronic hepatitis B, hepatitis C, alcoholic liver disease and non-alcoholic liver disease leads to fibrosis. Hepatocyte damage due to liver injury leads to the release of pro-fibrotic factors from infiltrated inflammatory cells, especially macrophages resulting in the activation of key pathogenic cells i.e. hepatic stellate cells. So, his PhD research now is focused on how to inhibit inflammatory macrophages using nanoparticles. His project is funded by LPDP fellowship, Indonesia.