E-mail: a.khurana@utwente.nl Telephone: +31 53 489 9665 Fax: +31 53 489 3511 Address: Faculty of Science and Technology Medical Cell BioPhysics (MCBP) Building: Carré Room: CR4435
Biography
Amit received his M.S. (Pharm.) degree in Pharmacology and Toxicology from the National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India, in 2014. In the same year, he began Ph.D. work as a NIPER fellow at NIPER, Hyderabad, India (2014-20). In 2017, he also received a fellowship from the DST (India) and DAAD (Germany) to work on a liver targeting formulation for the therapy of liver fibrosis (RWTH Aachen, Aachen, Germany). Further, he worked as a DBT-CNPq research fellow in an Indo-Brazil collaborative project (2016-19, University of Sau Paulo, Brazil). For his PhD thesis, he worked on novel therapeutics for the treatment of acute and chronic pancreatitis. Currently, he is working as a Research Scientist at the Centre for Biomedical Engineering (CBME), Indian Institute of Technology, Delhi on an artificial skin substitute for the management of second degree burn wound injury. Amit will join TLR in May 2021 as a DAAD PRIME fellow.
Amit will focus on mechanistic targeting of non-alcoholic steatohepatitis (NASH). NASH is the leading cause of liver transplantation and the pathological mechanisms of NASH remain still elusive. In this project, he will study the pathological role of the lipoxygenases (LOX) in the progression of NASH. This project is a unique collaboration combining fundamental liver research (with Prof. Ralf Weiskirchen, RWTH Aachen) and translational liver targeting research (At TLR, UT) contributing towards improved understanding of disease pathogenesis and a novel (nano) therapeutic for the treatment of NASH.